HighQualityMelengestrolacetate(CASNo.2919-66-6)MGAwithUSPassuredSynonyms:0-dione,17-(acetyloxy)-6-methyl-16-methylene-pregna-6-diene-3;6-dehydro-16-methylene-6-methyl-17-acetoxyprogesterone;ProductDescriptionMelengestrolacetateProductname:MelengestrolacetateCASRegistryNumber:2919-66-6Assay:98%Packaging:1kg/bagMolecularFormula:C25H32O4Molecularweight:396.52Appearance:Lightyellowcrystallinepowderskype:tracy665emailtracyatycphardotcomDescription:MGAsuppressedestrusandovulation,andresultedinthepresenceintheovary,afterregressionofcorporalutea,ofanincreasednumberoflargefollicles.Thelargestfolliclescorrespondinginstructuretodevelopingproestrous,matureestrous,orearlyatreticfolliclescontainedhypertrophiedthecainternacellsshowinglipidsecretionsignsandultrastructuralcharacteristicsofsteroidsynthesis.Themajorityofthelargestfollicles,however,wereatreticorlateatreticanddidnotcontainsteroid-typecells.Thedevelopmentofreplacementfollicleswasevidentinovarieswithlateatreticlargestfollicles.Theweight-gaineffectofMGAmaythereforebeassociatedwithasteroidogenic,probablyestrogenic,effectinthecow.Applicati***:Melengestrolacetate,sometimesabbreviatedasMGA,isasteroidalprogestinandantineoplasticagent.Itisnotapprovedforuseinhumans,andisinsteadusedasafeedadditivetopromotegrowthincattle,apurposeitislicensedforintheUnitedStatesandCanada.Itisanacetateesterofmelengestrol,whichincontrast,isnotusedineitheranimalsorhumans.Asynchronizationregimeinvolvescombiningtheeffectsofmelengestrolacetate(MGA),aprogestogen-likecompound,withPGF2a.Whenadministeredinthefeedatalevelof.5mg.perheadperday,MGAisveryeffectiveatpreventingcowsfromcomingintoheat.WhenPGF2aisadministeredfollowingMGAremoval,cowsexperienceatightlysynchronizedestrus.)