NaturalSexHormonePowderEstradiolvalerateCAS:979-32-8Name:EstradiolvalerateCAS:979-32-8Synonyms:Estradiolvalerate;OestradiolValerate;estradiol-17-valerate;1,3,5(10)-estratriene-3,17b-diol17-pentanote;EstradiolValeate;3-hydroxyestra-1,3,5(10)-trien-17-ylpentanoate;(17beta)-3-hydroxyestra-1,3,5(10)-trien-17-ylpentanoate;(8xi,9xi,14xi,17beta)-3-hydroxyestra-1,3,5(10)-trien-17-ylpentanoateMolecularFormulaC23H32O3MolecularWeight356.50EINECS213-559-2Meltingpoint144ºCBoilingpoint:486.2°Cat760mmHgFlashpoint:191.1°CRefractiveindex:1.567Appearance:Whiteoralmost-white,crystallinepowderorcolorlesscrystalsDensity:1.13g/cm3VapourPressure:4.47E-10mmHgat25°CDescription:Estrogensh***ebeenreportedtoincreasethechanceofwomb(endometrial)cancerinwomenwhoh***ebeenthroughmenopause,especiallyinwomenwhoreceiveestrogen-onlyhormonetherapy.Contactyourdoctorimmediatelyifyouexperienceanyunusualvaginalbleeding.Estrogensmayalsoincreasetheriskofcanceroftheovaryorbreast.Estrogen-containingproductsshouldnotbeusedtopreventheartdisease.Estrogengivenwithanotherhormone(progestin)forreplacementtherapycaninfrequentlycauseheartdisease(eg,heartattacks),stroke,seriousbloodclotsinthelegsorlungs(pulmonaryemboli***/deepveinthrombosis),dementia,andcancerofthebreast.Theserisksappeartodependonthelengthoftimeestradiolvalerateisusedandtheamountofestrogenperdose.Therefore,estradiolvalerateshouldbeusedfortheshortestpossiblelengthoftimeatthelowesteffectivedosesothatyouobtainthebenefitsandminimizethechanceofserioussideeffectsfromlong-termtreatment.C***ultyourdoctororpharmacistfordetails.Apllication:Treatingcertainsymptomsofmenopause(eg,hotflashes,vaginalitching,burning,ordryness).Itisusedtotreatlowlevelsofestrogencausedbycertainconditi***.Itmaybeusedtotreatcertaintypesofprostatecancer(advancedandrogen-dependent).Itmayalsobeusedforotherconditi***asdeterminedbyyourdoctor.Estradiolvalerateisafemaleestrogenhormone.Itworksbyreplacingnaturalestrogensinawomanwhocannolongerproduceenoughworksforadvancedprostatecancerbyantagonizingmalehormones.COA:TestsSpecificati***ResultsDescriptionWhiteCrystallinepowderWhiteCrystallinepowderIdentificationIRPositiveMeltingpointMeltingrangebetween143～150℃149.5¡æSpecificrotationSpecificrotation+41¡ãto+47¡ã+46.5¡ãLimitofEstradiol¡Ü1.0%0.4%Ordinaryimpurities¡Ü2.0%PassedWater¡Ü0.1%0.08%FreeAcid¡Ü0.5%0.35%Assay98.0～102.0%(onthedriedbasis)99.8%)