Flurogestone acetate
CAS2529-45-5NoSideEffectAntiInflammatoryGlucocorticoidSteroidsFlurogestoneAcetateHighQualityFlurogestoneacetate(CASNo.2529-45-5)withUSPassuredFlurogestoneacetateisapregnane.Alsoknownas:SureCN281973,ZINC04369857MolecularFormula:C23H31FO5MolecularWeight:406.487643skype:tracy665emailtracyatycphardotcomDescription:FluorogestoneAcetate(alsoknownasFlurogestoneAcetate,FlugestoneAcetate,FluorogesteroneAcetate)wasfirstsynthesisedbyG.D.SearleandCompanyin1959.Thechemical,whichhasprogestogenactivity,wasidentifiedasSC-9880.TheuseofSC-9880inanintr***aginaldeviceforthecontrolandsynchronizationofoestrusinsheepwasdescribedbyWishartFluorogestoneacetateshowedahighpotencywithshortdurationofactivityandperformedphysiologicallysimilartoprogesterone.FGAwasapproximately20-25timesmorepotentthanprogesterone.Flurogestoneacetatewasshowntobereadilyabsorbedfromimpregnatedsponges.A30mgimpregnatedspongewaseffectiveinblockingovulationandoestrus,oncethespongewasremovedimpregnatedewesshowedvisibleoestrus,andifinseminated2to4daysafterspongeremovalshowedhighconceptionrates.Specificati***:ProductnameFlurogestoneacetateAppearanceWhitecrystallinepowderChromatographicpurityAnyindividualimpuritynotmorethan1.0%Totalimpuritiesnotmorethan2.0%0.4%1.3%LossondryingNotmorethan0.5%0.2%ResidueonignitionNotmorethan0.2%0.03%ResidualsolventsMethanol¡Ü3000ppmMethyleneChloride¡Ü600ppmChloroform¡Ü60ppmTetrahydrofuran¡Ü720ppm370ppmNotdetectoutNotdetectoutNotdetectoutAssayBetween97.0%and102.0%99.3%Micronixation90%notmorethan10micr***90%notmorethan10aicr***)