whitecrystallineestrogensolidMestranol98%usedtopreventpregnancyAnabolicsteroidMestranol72-33-3Synonyms:Mestranolpowder;Inostral;MestranolCAS:72-33-3Formula:C21H26O2MolecularWeight:310.47EINECS:200-777-8MeltingPoint:153-155°C(lit.)Appearance:CrystallinesolidPurity:>99%PackAge:AluminiumfoilbagpackingStorage:Keepincoolanddryplace,awayfromlight.QuickDetail:ProductnameMestranolOthername2-Methyl-4-trimethylsilyl-3-butyn-2-olCASNo72-33-3MFC8H16OSiMW156.2975Purity98%AppearancewhitecrystallinesolidDescription:Mestranolisthe3-methyletherofethinylestradiol.Itwastheestrogenusedinmanyofthefirstoralcontraceptives.Itisabiologicallyinactiveprodrugofethinylestradioltowhichitisdemethylatedintheliverwithaconversionefficiencyof70%(50µgofmestranolispharmacokineticallybioequivalentto35µgofethinylestradiol).Mestranolisthe3-methyletherofethinylestradiol.Ethinylestradiol,isasyntheticderivativeofestradiol.Ethinylestradiolisorallybio-activeandtheestrogenusedinalmostallmodernformulati***ofcombinedoralcontraceptivepills.Itbindsto(andactivates)theestrogenreceptor.Mestranolisabiologicallyinactiveprodrugofethinylestradioltowhichitisdemethylatedintheliverwithaconversionefficiencyof70%.Estrogensdiffuseintotheirtargetcellsandinteractwithaproteinreceptor.Targetcellsincludethefemalereproductivetract,themammarygland,thehypothalamus,andthepituitary.Estrogensincreasethehepaticsynthesisofsexhormonebindingglobulin(SHBG),thyroid-bindingglobulin(TBG),andotherserumproteinsandsuppressfollicle-stimulatinghormone(FSH)fromtheanteriorpituitary.Thecombinationofanestrogenwithaprogestinsuppressesthehypothalamic-pituitarysystem,decreasingthesecretionofgonadotropin-releasinghormone(GnRH).Applicati***:Thiscombinationhormonemedicationisusedtopreventpregnancy.Itcontains2hormones:aprogestinandanestrogen.Itworksmainlybypreventingthereleaseofanegg(ovulation)duringyourmenstrualcycle.Italsomakesvaginalfluidthickertohelppreventspermfromreachinganegg(fertilization)andchangestheliningoftheuterus(womb)topreventattachmentofafertilizedegg.Ifafertilizedeggdoesnotattachtotheuterus,itpassesoutofthebody.Besidespreventingpregnancy,birthcontrolpillsmaymakeyourperiodsmoreregular,decreasebloodlossandpainfulperiods,decreaseyourriskofovariancysts,andalsotreatacne.Usingthismedicationdoesnotprotectyouoryourpartneragainstsexuallytran***itteddiseases(suchasHIV)