6-Aminocaproic Acid
6-AminocaproicAcidSpecificati***1.6-Aminocaproicacid2.CAS:60-32-23.Fastdelivery4.standard:USP32、JP、EP6Description:Aminocaproicacid(alsoknownasAmicar,-aminocaproicacid,-Ahx,or6-aminohexanoicacid)isaderivativeandanalogueoftheaminoacidlysine,whichmakesitaneffectiveinhibitorforenzymesthatbindthatparticularresidue.Suchenzymesincludeproteolyticenzymeslikepla***in,theenzymeresp***ibleforfibrinolysis.Forthisreasonitiseffectiveintreatmentofcertainbleedingdisorders,anditismarketedasAmicar.AminocaproicacidisalsoanintermediateinthepolymerizationofNylon-6,whereitisformedbyring-openinghydrolysisofcaprolactamWhitetoyellowishcrystallinepowder,easilysolubleinwater,slightlysolubleinmethylalcohol,insolubleinethylalcoholandether,odorless,bittertaste.Usage:Itisagoodastringentagainstfibrinolytic,canbeusedin/with:1.Surgerybleeding2.Gynecologyandobstetricsbleeding3.Pneumorrhagia4UppergastrointestinalhemorrhageClinicaluseAminocaproicacidisusedtotreatexcessivepostoperativebleeding,especiallyafterproceduresinwhichagreatamountofbleedingisexpected,suchascardiacsurgery.Itcanbegivenorallyorintr***enously.Ameta-analysisfoundthatlysineanalogslikeaminocaproicacidsignificantlyreducedbloodlossinpatientsundergoingcoronaryarterybypassgrafting.Aminocaproicacidcanalsobeusedtotreattheoverdoseand/ortoxiceffectsofthethrombolyticpharmacologicagentstissuepla***inogenactivator(commonlyknownastPA)andstreptokinase.)