Ethinyl Estradiol
EthinylEstradiolskype:tracy665emailtracyatycphardotcomCAS:57-63-6Standard:USP34Purity:99.85%COAis***ailableChemicalname:3-hydroxy-19-toa-17alphapregnane-1,3,5(10)-threeene-20-alkyne17alcoholProperties:whitetocreamwhitecrystallinepowder.Meltingpointof145-146°C(semi-hydrate).182-184°C(anhydrous).Solubleinethanol,practicallyinsolubleinwater.Odorless.Theuseofethinylestradiol:estrogenclass.ethinylestradiolforestrogendrugs.Effectofdiethylstilbestrol,butethinylestradiol20timesaspotent.EnglishName:EthinylestradiolMolecularformula:C20H24O2Molecularweight:296.41EINECS:200-342-2Traits:ethinylestradiolTCiswhiteoroff-whitecrystallinepowder;odorless.Solubleinethanol,isopropylalcoholorether,solubleinchloroform,insolubleinwater.Conclusion:TheproductcomplieswithspecificationinUSP34Description:1,supplementthelackofestrogen,thetreatmentoffemalesexualdysfunction,menopause,menopausalsyndrome;(foradvancedbreastcancerinpostmenopausalwomen),inthetreatmentofadvancedprostatecancer;combinedwithprogestogensdrug,caninhibitovulation,canbeusedasacontraceptive.Clinicalmainlyforinhibitingovulationmedicine;alsousedinchildrenwithcryptorchidi***andhyperandrogeni***,pituitarytumor.Forthediagnosisofhypothalamus-pituitary-gonadaldysfunction,accordingtothevariationofsexhormoneandsexhormonelevels.2,treatmentofhypogonadotropichypogonadi***inducedamenorrheaandinfertilityinfertility,multipleovarianfollicles.Withtheweightlossrelatedamenorrhea,shouldusethecorrectweightdiet.Alsousedforprostatecancer(oftenusedincombinationwithcyproteroneorfluorinebenzoylimide),delayedpubertyorearlyandendometrialdifferent.Mainlyusedtoinhibitovulation,achievethepurposeofcontraception.Pharmacologicaleffects:ethinylestradiolinthehypothalamusandpituitaryarepositive,negativefeedbackeffect,***alldosagecanstimulategonadotropinsecretion;highdoseinhibitsthesecretion,therebyinhibitingovarianoviposit,achievetheantifertilityeffect.Thisproductcanstimulatethesynthesisandsecretionofpituitarygonadotropin(FSHandLH),gonadotropinstimulatedgonadotropinreleasinghormone.Thehypothalamusgonadotropin-releasinghormoneregulatedbymanykindsoffactors,includingsexhormonesinthecirculation.Singleagentsusecanincreasesexualhormoneincirculation;continuoususecancauseadenohypophysisgonadotropin-releasinghormonereceptordown-regulation,therebyreducingthesecretionofsexhormones.)