中文名称：兔抗人、大、小鼠等活化半胱胺酸蛋白酶蛋白-3***英文名称：Anti-Caspase-3(Active)其他名称：Caspase-3subunitp17;APOPAIN;CASP3;Caspase3apoptosisrelatedcysteineprotease;Caspase3;CPP32;CPP32B;CysteineproteaseCPP32;HumancysteineproteaseCPP32isoformalphamRNAcompletecds;PARPcle***ageprotease;SCA1;SCA1;SREBPcle***ageactivity1;Yama;CASP3_HUMAN;Caspase-3;CASP-3;Apopain;ProteinYama;SREBPcle***ageactivity1;SCA-1.产品品牌：Pllabs产品编号：PL030081R产品规格：0.1mg/0.2mg产品包装：一支包装（原装进口、进口分装）​免疫原：KLHconjugatedsyntheticpeptidederivedfromhumanCaspase-3(Active)N-terminus***类型：RabbitPolyclonalIgG背景介绍：Thecaspasefamilyofcysteineproteasesplayakeyroleinapoptosis.Caspase3isthemostextensivelystudiedapoptoticproteinamongcaspasefamilymembers.Caspase3issynthesizedasinactiveproenzymethatisprocessedincellsundergoingapoptosisbyselfproteolysisand/orcle***agebyotherupstreamproteases(e.g.Caspases8,9and10).TheprocessedformofCaspase3c***istsoflarge(17kDa)and***all(12kDa)subunitswhichassociatetoformanactiveenzyme.Caspase3iscle***edatAsp28Ser29andAsp175Ser176.TheactiveCaspase3proteolyticallycle***esandactivatesothercaspases(e.g.Caspases6,7and9),aswellasrelevanttargetsinthecells(e.g.PARPandDFF).Alternativesplicingofthisgeneresultsintwotranscriptvariantswhichencodethesameprotein.InimmunohistochemicalstudiesCaspase3expressionhasbeenshowntobewidespreadbutnotpresentinallcelltypes(e.g.commonlyreportedinepithelialcellsofskin,renalproximaltubulesandcollectingducts).DifferencesinthelevelofCaspase3h***ebeenreportedincellsofshortlivednature(eggerminalcentreBcells)andthosethatarelonglived(egmantlezoneBcells).Caspase3isthepredominantcaspaseinvolvedinthecle***ageofamyloidbeta4Aprecursorprotein,whichisassociatedwithneuronaldeathinAlzheimer'sdisease.ReactswithCaspase-3subunitp17andprecursor.应用范围：Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep（Pleasedecidethespecificitybyhomology）更多产品：（加拿大PLlabs公司***）其他产品：（华拓生物中文网）------------------------------------------------------------------------------------------联系人：李先生手机：15217723134电话：0755-36953798传真：0755-86372180邮箱：lilyn@深圳市豪地华拓生物科技有限公司网址：http://地址：深圳市南山区创业路中兴工业城5栋518)