中文名称：基质金属蛋白酶-1***英文名称：Anti-MMP-1产品编号：PL030424R免疫原：KLHconjugatedsyntheticpeptidederivedfromhumanMMP1C-terminus***类型：RabbitPolyclonalIgG产品规格：0.1mg/0.2mg包装情况：一支包装（原装进口、分装）其他名称：CLGN;CLG;27kDainterstitialcollagenase;Fibroblastcollagenase;Interstitialcollagenase;MMP1;MMP;1Matrixmetallopeptidase1(interstitialcollagenase);MatrixMetalloproteinase1.背景介绍：Thematrixmetalloproteinases(MMPs)areafamilyofatleasteighteensecretedandmembraneboundzincendopeptidases.Collectively,theseenzymescandegradeallthecomponentsoftheextracellularmatrix,includingfibrillarandnonfibrillarcollagens,fibronectin,lamininandbasementmembraneglycoproteins.Ingeneral,asignalpeptide,apropeptide,andacatalyticdomaincontainingthehighlyc***ervedzincbindingsitecharacterizesthestructureoftheMMPs.Inaddition,fibronectinlikerepeats,ahingeregion,andaCterminalhemopexinlikedomainallowcategorizationofMMPsintothecollagenase,gelatinase,stomelysinandmembranetypeMMPsubfamilies.AllMMPsaresynthesizedasproenzymes,andmostofthemaresecretedfromthecellsasproenzymes.Thus,theactivationoftheseproenzymesisacriticalstepthatleadstoextracellularmatrixbreakdown.MMPsarec***ideredtoplayanimportantroleinwoundhealing,apoptosis,boneelongation,embryodevelopment,uterineinvolution,angiogenesisandtissueremodeling,andindiseasessuchasmultiplesclerosis,Alzheimer's,malignantgliomas,lupus,arthritis,periodontis,glumerulonephritis,atherosclerosis,tissueulceration,andincancercellinvasionandmetastasis.交叉反应物种：Human,Dog,Pig,Cow,Horse,Rabbit,GuineaPig,G（Pleasedecidethespecificitybyhomology）★☆★☆★深圳市豪地华拓生物科技有限公司★☆★☆★★☆★pllabs***：加拿大PLlabs公司网站★☆★-------------------------------------------------------------------------------------------联系人：李先生手机：15217723134电话：0755-36953798传真：0755-86372180邮箱：lilyn@深圳市豪地华拓生物科技有限公司网址：http://地址：深圳市南山区创业路中兴工业城5栋518)