中文名称：兔抗人、大、小鼠、猪、犬***坏死因子-α***英文名称：Anti-TNF-alpha产品编号：PL030078R免疫原：KLHconjugatedsyntheticpeptidederivedfromhumanTNFalpha***类型：RabbitPolyclonalIgG产品规格：0.1mg/0.2mg包装情况：一支包装（原装进口、分装）其他名称：TNF-alpha;APC1;Cachectin;DIF;Differentiationinducingfactor;Macrophagecytotoxicfactor;MCF;Necrosin;TNF-a;TNFalpha;TNF;TNFMacrophageDerived;TNFMonocyteDerived;TNFSuperfamilyMember2;TNFA;TNFSF2;Tumornecrosisfactorligandsuperfamilymember2;TumorNecrosisFactorPrecursor;TumourNecrosisFactorAlpha;TNFSF1A.背景介绍：GrowthFactorandHormonesTumorNecrosisFactorAlpha(TNFalpha)isaproteinsecretedbylipopolysaccharidestimulatedmacrophages,andcausestumornecrosiswheninjectedintotumourbearingmice.TNFalphaisbelievedtomediatepathogenicshockandtissueinjuryassociatedwithendotoxemia.TNFalphaexistsasamultimeroftwo,three,orfivenoncovalentlylinkedunits,butshowsasingle17kDabandfollowingSDSPAGEundernonreducingconditi***.TNFalphaiscloselyrelatedtothe25kDaproteinTumourNecrosisFactorbeta(lymphotoxin),sharingthesamereceptorsandcellularacti***.TNFalphacausescytolysisorcytostasisofcertaintransformedcells,beingsynergisticwith***gammainitscytotoxicity.Althoughithaslittleeffectonmanyculturednormalhumancells,TNFalphaappearstobedirectlytoxictovascularendothelialcells.Otheracti***ofTNFalphaincludestimulatinggrowthofhumanfibroblastsandothercelllines,activatingpolymorphonuclearneutrophilsandosteoclasts,andinductionofinterleukin1,prostaglandinE2andcollagenaseproduction.TNFalphaiscurrentlybeingevaluatedintreatmentofcertaincancersandAIDSRelatedComplex.交叉反应物种：Human,Dog,Pig,Horse,（Pleasedecidethespecificitybyhomology）★☆★☆★深圳市豪地华拓生物科技有限公司★☆★☆★★☆★abbiotec***：美国Abbiotec公司网站★☆★★☆★pllabs***：加拿大PLlabs公司网站★☆★★☆★荧光金：美国Fluorochrome公司网站★☆★★☆★***盒：加拿大DBC公司www.dbc-★☆★★☆★美国GSI公司网站http://★☆★-------------------------------------------------------------------------------------------联系人：李先生手机：15217723134电话：0755-36953798传真：0755-86372180邮箱：lilyn@深圳市豪地华拓生物科技有限公司网址：http://地址：深圳市南山区创业路中兴工业城5栋518)