CatalogNumber:PL030581RQuantitysize:0.1ml(1mg/1ml.Rec***titutewith0.1mlsteriledistilledwater.)Immunogen:KLHconjugatedsyntheticpeptidederivedfrommouseIL-4C-terminusClonality:RabbitPolyclonalIgGPurity:affinitypurifiedbyProteinAForm:LyophilizedorLiquidStorageBuffer:0.01MPBS,pH7.4with10mg/mlBSAand0.1%SodiumazideBackground:Interleukin4isapleiotropiccytokineproducedbyactivatedTcells,mastcellsandbasophils.ItisaligandforInterleukin4receptor.TheInterleukin4receptoralsobindstoIL13,whichmaycontributetomanyoverlappingfuncti***ofthiscytokineandIL13.IL4elicitsmanydifferentbiologicalresp***es,buthastwodominantfuncti***.ThefirstisregulatingdifferentiationofnatveCD4+TcelltotheTh2type.Th2cellsproduceIL4,IL5,IL10andIL13,whichtendtof***orahumoralimmuneresp***ewhilesuppressingacellmediatedimmuneresp***econtrolledbyTh1cells.STAT6,asignaltransducerandactivatoroftranscription,hasbeenshowntoplayacentralroleinmediatingtheimmuneregulatorysignalofthiscytokine.ThesecondisregulatingIgEandIgG1productionbyBcells.Twoalternativelysplicedtranscriptvariantsofthisgeneencodingdistinctisoformsh***ebeenreported.Alsoknownas:Bcellgrowthfactor1;BcellIgGdifferentiationfactor;BCellStimulatoryFactor1;BCGF1;BCGF1;Binetrakin;BSF1;BSF1;HCGF;Hodgkin’sCellGrowthFactor;IAInducingFactor;IGG1inductionfactor;IL4;Il4e12;Interleukin4;Interleukin4,isoform1;Interleukin4;Lymphocytestimulatoryfactor1;Macrophagefusionfactor;Mastcellgrowthfactor2;MCGF2;MFF;MGC79402;Pitrakinra;Tcellgrowthfactor2;TCGF2.predictedmolecularweight:14kDaSpecificityReaction:Mouse,Rat,（Pleasedecidethespecificitybyhomology）Application:·WB=1:100-500·ELISA=1:500-1000·IP=1:20-100·IHC-P=1:100-500·IHC-F=1:100-500·IF=1:100-500·Optimalworkingdiluti***mustbedeterminedbytheenduser.Storage:Storeat-20°Cforoneyear.***oidrepeatedfreeze/thawcycles.TheLyophilizedorLiquidantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.Whenrec***titutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplicati***.更多产品信息欢迎登陆http://查询)