(ProSpec)【mIL10】重组小鼠白介素-10产品报价￥800/2μg￥2080/10μg￥74880/1mg背景资料IL10isacytokineproducedprimarilybymonocytesandtoalesserextentbylymphocytes.Thiscytokinehaspleiotropiceffectsinimmunoregulationandinflammation.Itdown-regulatestheexpressionofTh1cytokines,MHCclassIIAgs,andcostimulatorymoleculesonmacrophages.ItalsoenhancesBcellsurvival,proliferation,andantibodyproduction.ThiscytokinecanblockNF-kappaBactivity,andisinvolvedintheregulationoftheJAK-STATsignalingpathway.Knockoutstudiesinmicesuggestedthefunctionofthiscytokineasanessentialimmunoregulatorintheintestinaltract.产品描述小鼠白介素-10重组蛋白是在大肠***中重组表达的，是一条单链、非糖基化的多肽链，包含有161个氨基酸，分子量为18785Da。该小鼠白介素-10重组蛋白***终由标准的色谱技术纯化出。来源宿主大肠***中重组表达序列ThesequenceofthefirstfiveN-terminalaminoacidswasdeterminedandwasfoundtobeMet-Ser-Arg-Gly-Gln.溶解建议提供的小鼠白介素-10(mIL10)产品为过滤灭菌的白色冻干粉末；该冻干粉末是从含小鼠白介素-10(mIL10)的PBS溶液中经进一步透析并冻干产生的。我们建议加无菌的18MΩ-cm水以配制工作储存液到100μg/ml，后继实验过程中可根据实验要求进一步稀释。保存建议小鼠白介素-10(mIL10)在室温可保存3周，或置于-18℃冻存用于长期保存。重新溶解后可以在4℃冷藏保存至少2-7天；如果想延长保存时间，建议分装（加载体蛋白如0.1%HSA或BSA）后置于-18℃冻存。请避免反复冻融。)