脑（Alzheimer'sdisease,AD）是由于***退行性变、脑血管病变、***、外伤、***、营养代谢障碍等多种原因引起的一组***群，是***在意识清醒的状态下出现的持久的***的智能减退，表现为***、计算力、判断力、注意力、抽象思维能力、语言功能减退，情感和行为障碍，***生活和工作能力丧失。脑退化症根据其病因主要分为脑变性***引起的***呆——阿尔茨海默病性***呆（又叫脑退化，Alzheimer’sDisease，简称AD）、脑血管病引起的***呆（血管性***呆，VascularDentia,简称VaD）、混合性***呆(MixedDementia，简称MixD）三大类。其次还包括路易小体***呆（DementiawithLewyBodies，简称DLB），额颞叶***呆（FrontotemporalDementia，简称FTD），***病性***呆（Parkinson’sDisease，简称PD），克罗伊茨费尔特-雅各布病***呆（Creutzfeldt-JakobDisease，简称CJD），正常颅压***性***呆（NormalPressureHydrocephalus，简称NPH），韦-科二氏******呆（Wernicke-KorsakoffSyndrome，简称WKS），由***Bl2、叶酸缺乏所致的***呆等。[1]J56701299Amyloidbeta-ProteinImmunohistostainKitβ淀粉样蛋白******染色***盒50T利用检测AβC末端的***染色Aβ40和Aβ42***切片J57301299PhosphorylatedTauImmunohistostainKit磷酸化τ******染色***盒100T染色***切片中的超磷酸化τ蛋白（如***纤维病变***）J20281014AntiPhosphorylatedalpha-Synuclein,MonoclonalAntibody；抗磷酸化α突触核蛋白单抗50uL特异性针对人σ突触核蛋白包括磷酸化Ser129J18761019Amyloidbeta-Protein(1-40)β淀粉样蛋白(1-40)1mg多肽J18951014Amyloidbeta-Protein(1-40)(Hydrochloride)β淀粉样蛋白(1-40)，冻干粉1mg多肽冻干粉J18771016Amyloidbeta-Protein(1-42)β淀粉样蛋白(1-42)0.5mg多肽J18961011Amyloidbeta-Protein(1-42)(Hydrochloride)β淀粉样蛋白(1-40)，冻干粉1mg多肽冻干粉8952487β-Amyloid(1-42),humanβ淀粉样蛋白(1-42)，人0.5mgC203H311N55O60S8952487β-Amyloid(1-42),humanβ淀粉样蛋白(1-42)，人2.5mgC203H311N55O60S8953771β-AmyloidPeptide(1-42),ratβ淀粉样多肽(1-42)，大鼠0.5mgC199H307N53O59S[107761-42-2]8953771β-AmyloidPeptide(1-42),ratβ淀粉样多肽(1-42)，大鼠2.5mgC199H307N53O59S[107761-42-2]8953770β-Amyloid(1-40),ratβ淀粉样蛋白(1-40)，大鼠0.5mgC190H291N51O57S[131438-79-4]8953770β-Amyloid(1-40),ratβ淀粉样蛋白(1-40)，大鼠2.5mgC190H291N51O57S[131438-79-4]8951516β-Amyloid(1-40),UltraPure,TFAβ淀粉样蛋白(1-40)，超纯，TFA0.5mgC194H295N53O58S8951516β-Amyloid(1-40),UltraPure,TFAβ淀粉样蛋白(1-40)，超纯，TFA2.5mgC194H295N53O58Sβ淀粉样蛋白片断,Amyloidβ-ProteinFragmentsJ43071330Amyloidβ-Protein(Human,1-40)0.5mg4307-VJ43791336Amyloidβ-Protein(Human,1-40)[HClForm]0.5mg4379-VJ43491338Amyloidβ-Protein(Human,1-42)0.5mg4349-VJ43701333Amyloidβ-Protein(Human,1-43)0.5mg4370-VJ43591334Amyloidβ-Protein(Human,1-16)0.5mg4359-VJ43091334Amyloidβ-Protein(Human,25-35)0.5mg4309-VJ43671336Amyloidβ-Protein(Human,3-42)0.5mg4367-VJ43581337β-SheetbreakerpeptideiAβ55mg4358-Vβ淀粉样蛋白对照多肽，Amyloidβ-ProteinControlPeptideJ44131332Amyloidβ-Protein（40-1）0.1mg4413-SJ44201337Amyloidβ-Protein（42-1）0.1mg4420-Sa-分泌酶阻断剂,Alpha-secretaseinhibitorJ43781339LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE1mg4378-Vβ-分泌酶阻断剂,β-secretaseinhibitorJ32121334MOCAC-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-LYS(DNP)-ARG-A1mg3212-VJ65811556β-secretaseactivitykit100Tγ-分泌酶阻断剂,γ-secretaseinhibitorJ43941333L-685,4581mg4394-VJ32191333(3,5-Difluorophenylacetyl)-Ala-Phg-OBut5mg3219-Vγ-分泌酶底物,γ-secretaseSubstrateJ32171339Nma-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH21mg3217-V抗***,antiserumJ00231330Amyloidβ-Protein(Human,1-16)antiserum50ul14359-VJ00111330Amyloidβ-Protein(Human,1-40)antiserum50ul14307-VJ00211336Amyloidβ-Protein(Human,34-40)antiserum50ul14356-VJ00221333Amyloidβ-Protein(Human,37-42)antiserum50ul14357-VJ00491334Amyloidβ-Protein(Human,37-43)antiserum50ul14414-V其他J13551197Schizandrin；***素20mgJ10441192SchizandrinStandard；***素标准品20mgJ04951077GomisinAStandard；***醇甲标准品10mgJ04961074GomisinNStandard；***酯N标准品10mgJ01801151OstholeStandard；***素20mg脑退化症症多起病于老年期，潜隐起病，病程缓慢且不可逆，临床上以智能损害为主。病理改变主要为皮质弥漫性萎缩，沟回增宽，脑室扩大，***元大量减少，并可见老年斑（SP），***原纤维结（NFT）等病变，***乙酰化酶及乙酰***含量显著减少。起病在65岁以前者旧称老年病前期***呆，或早老性***呆，多有同病家族史，病情发展较快，颞叶及顶叶病变较显著，常有失语和失用。65岁以上发病者称晚发型***呆，多为散发，病变发展较慢，研究发现，除了发病年龄早晚有区别外，它们在临床症状和脑病理改变方面明显不同。上海西宝生物科技有限公司联系人：李丹萍手机:13817370083;电话：021-50272978-6512传真:021-50272982***:2457655304MSN:lifesci10@E-mail:lifesci10@http://;地址:上海张江高科技园区毕昇路299号11-502#邮编:201204)