PEG修饰服务——蛋白修饰,药物研发新纪元
蛋白质修饰——PEG修饰服务蛋白质药物用于人类疾病的治疗近几年得到飞速发展,但蛋白质药物却存在诸如半衰期短、高免疫原性、低溶解性、易被酶水解等弊端。用PEG(聚乙二醇)修饰这些蛋白质分子,能明显消除这些不利因素,成为延长蛋白质半衰期,改变其药代动力学特性与免疫原性的有效手段。可以用于PEG修饰的目标蛋白质包括重组蛋白质、合成的肽段、抗体片段等。蛋白质修饰(PEG修饰)具有广阔的应用前景,迄今为止,已经有十个PEG修饰的蛋白质药物通过美国FDA批准上市。有效的进行蛋白质修饰/PEG修饰的关键步骤包括:一、选择合适的PEG分子以获得较好的药代动力学特性。二、选择可靠的供应商以保障原料来源的品质及稳定性。三、选择恰当的反应基团以保障修饰位点的特异性从而最大限度的保持药物的生物学活性。四、选择最佳的修饰条件如缓冲液体系、pH、时间等,以保障尽量高的修饰率与活性保留比例、降低原料成本。五、建立合理的分离工艺,去除未修饰蛋白的残留。由于PEG修饰总是会导致蛋白质活性的下降,高活性的痕量未修饰蛋白会严重干扰修饰后样品的活性,并导致用药时的困难。·蛋白质修饰可提供服务:一、PEG选择:评价PEG是否合适的标准包括药代动力学参数、目标蛋白活性保留程度、免疫原性、修饰效率、可放大性与成本等。二、PEG修饰蛋白质制备:在完成PEG选择步骤后,欣百诺可以为您进行工艺放大并制备您需要的PEG修饰蛋白。我们可以提供毫克到克级的修饰蛋白。我们也可以提供符合中国GLP/GMP标准的大规模样品生产,供您临床前研究与临床研究。三、中试/大规模PEG修饰过程开发:欣百诺的过程开发服务可以为您提供工业规模的PEG修饰工艺,并按照药品要求建立修饰后的目标蛋白质纯化工艺。所建立的技术工艺与相关知识产权可以归客户所有。上海西宝生物科技有限公司杨露(6221)13512172575QQ:1916572322俞婵(6512)13817370083QQ:2457655304杨树彦(6236)13788987962QQ:1961275959电话:021-50272975/76/77/78传真:021-50272982E-mail:trade@lifesci9@MSN:lifesci9@Http://地址:上海市张江高科技园区毕升路299弄11#502【修饰性PEG】修饰性PEG又叫修饰性聚乙二醇,是经过化学修饰基团或者生物活性基团修饰的PEG。在药物开发研究中,为了增加蛋白或多肽药物在体内半衰期,降低免疫原性,同时增加药物的水溶性,使用有化学基团修饰的PEG与蛋白药物共价结合,与蛋白结合之前的带有修饰性基团的PEG就是修饰性PEG。【修饰性PEG的修饰基团】:氨基(-Amine)-NH2,氨甲基-CH2-NH2,马来酰亚胺-Mal,羧基-COOH,巯基(-Thiol)-SH,丙醛-ALD,琥珀酰亚胺碳酸酯-SC,琥珀酰亚胺乙酸酯-SCM,琥珀酰亚胺丙酸酯-SPA,琥珀酰亚胺琥珀酸酯-SS,琥珀酰亚胺-NHS,二硫吡啶基-OPSS,丙酸基-CH2CH2COOH,醛基-CHO,正吡啶二硫基-S-S-Pyridine,巯酯基-VS,丙烯酸基-Acrylate,丙烯酸基-AC,叠氮基-Azide,生物素基-Biotin,环氧基-EP,荧光素基-Fluorescein,戊二酸基-GA,酰肼基-Hydrazide,炔基-Alkyne,对硝基苯碳酸酯基-NPC,异氰酸基-NCO,邻二硫吡啶基-OPSS,硅烷基-Silane,-SVA,BOC-,羧甲基-CM,Fmoc-NH-。张江高科技园区杨露13512172575。上海Seebio代理LaysanBio、CreativePEGWorks、IrisBiotechCfm、NOF日油等不同规格的修饰性PEG,进口原装,1~2周货期,可供应mg-kg级别的修饰性PEG。【常用的修饰性PEG】Seebio货号货号品名包装LP-0014arm-PEG-ACRL-10K-1g4arm-PEG-ACRL,MW10kDa1gLP-0024arm-PEG-ACRL-20K-1g4arm-PEG-ACRL,MW20kDa1gLP-0034arm-PEG-ACRL-20K-5g4arm-PEG-ACRL,MW20kDa5gLP-0044arm-PEG-CM-10K-1g4arm-PEG-CM,MW10kDa1gLP-0054arm-PEG-CM-10K-5g4arm-PEG-CM,MW10kDa5gLP-0064arm-PEG-EPOX-10K-5g4arm-PEG-Epoxide,MW10kDa5gLP-0074arm-PEG-EPOX-20K-1g4arm-PEG-Epoxide,MW20kDa1gLP-0074arm-PEG-EPOX-20K-5g4arm-PEG-Epoxide,MW20kDa5gLP-0084arm-PEG-MAL-10K-1g4arm-PEG-MAL,MW10kDa1gLP-0094arm-PEG-MAL-20K-1g4arm-PEG-MAL,MW20kDa1gLP-0104arm-PEG-NH2-10K-1g4arm-PEG-NH2,MW10kDa1gLP-0104arm-PEG-NH2-10K-5g4arm-PEG-NH2,MW10kDa5gLP-0114arm-PEG-NH2-20K-1g4arm-PEG-NH2,MW20kDa1gLP-0114arm-PEG-NH2-20K-5g4arm-PEG-NH2,MW20kDa5gLP-0124arm-PEG-SCM-10K-1g4arm-PEG-SCM,MW10kDa1gLP-0124arm-PEG-SCM-10K-5g4arm-PEG-SCM,MW10kDa5gLP-0134arm-PEG-SH-10K-1g4arm-PEG-Thiol,MW10kDa1gLP-014ACRL-PEG-ACRL-1000-1gAcrylate-PEG-Acrylate,MW1,0001gLP-015ACRL-PEG-ACRL-10K-1gAcrylate-PEG-Acrylate,MW10kDa1gLP-016ACRL-PEG-ACRL-2000-1gAcrylate-PEG-Acrylate,MW2,0001gLP-017ACRL-PEG-ACRL-20K-1gAcrylate-PEG-Acrylate,MW20kDa1gLP-018ACRL-PEG-ACRL-3400-1gAcrylate-PEG-Acrylate,MW3,4001gLP-018ACRL-PEG-ACRL-3400-5gAcrylate-PEG-Acrylate,MW3,4005gLP-019ACRL-PEG-ACRL-5000-1gAcrylate-PEG-Acrylate,MW5,0001gLP-019ACRL-PEG-ACRL-5000-5gAcrylate-PEG-Acrylate,MW5,0005gLP-020ACRL-PEG-MAL-3400-1gAcrylate-PEG-Maleimide,MW3,4001gLP-021ACRL-PEG-SCM-2000-1gAcrylate-PEG-SCM,MW2,0001gLP-021ACRL-PEG-SCM-2000-500mgAcrylate-PEG-SCM,MW2,000500mgLP-022ACRL-PEG-SCM-3400-1gAcrylate-PEG-SCM,MW3,4001gLP-022ACRL-PEG-SCM-3400-500mgAcrylate-PEG-SCM,MW3,400500mgLP-023ACRL-PEG-SCM-5000-1gAcrylate-PEG-SCM,MW5,0001gLP-024ACRL-PEG-SVA-3400-1gAcrylate-PEG-SVA,MW3,4001gLP-024ACRL-PEG-SVA-3400-500mgAcrylate-PEG-SVA,MW3,400500mgLP-025bALD-PEG-bALD-10K-1gButyrAldehyde-PEG-ButyrAldehyde,MW10kDa1gLP-025bALD-PEG-bALD-10K-5gButyrAldehyde-PEG-ButyrAldehyde,MW10kDa5gLP-026bALD-PEG-bALD-20K-1gButyrAldehyde-PEG-ButyrAldehyde,MW20kDa1gLP-026bALD-PEG-bALD-20K-5gButyrAldehyde-PEG-ButyrAldehyde,MW20kDa5gLP-027bALD-PEG-bALD-3400-1gButyrAldehyde-PEG-ButyrAldehyde,MW3,4001gLP-027bALD-PEG-bALD-3400-5gButyrAldehyde-PEG-ButyrAldehyde,MW3,4005gLP-028bALD-PEG-bALD-5K-1gButyrAldehyde-PEG-ButyrAldehyde,MW5,0001gLP-028bALD-PEG-bALD-5K-5gButyrAldehyde-PEG-ButyrAldehyde,MW5,0005gLP-029Biotin-PEG-MAL-3400-100mgBiotin-PEG-Maleimide,MW3,400100mgLP-029Biotin-PEG-MAL-3400-1gBiotin-PEG-Maleimide,MW3,4001gLP-029Biotin-PEG-MAL-3400-500mgBiotin-PEG-Maleimide,MW3,400500mgLP-030Biotin-PEG-MAL-5000-1gBiotin-PEG-Maleimide,MW5,0001gLP-031Biotin-PEG-NH2-2000-500mgBiotin-PEG-NH2,MW2,000500mgLP-032Biotin-PEG-NH2-3400-100mgBiotin-PEG-NH2,MW3,400100mgLP-032Biotin-PEG-NH2-3400-1gBiotin-PEG-NH2,MW3,4001gLP-033Biotin-PEG-NH2-5000-100mgBiotin-PEG-NH2,MW5,000100mgLP-033Biotin-PEG-NH2-5000-1gBiotin-PEG-NH2,MW5,0001gLP-034Biotin-PEG-SC-2000-100mgBiotin-PEG-SC,MW2,000100mgLP-034Biotin-PEG-SC-2000-1gBiotin-PEG-SC,MW2,0001gLP-035Biotin-PEG-SC-3400-100mgBiotin-PEG-SC,MW3,400100mgLP-035Biotin-PEG-SC-3400-1gBiotin-PEG-SC,MW3,4001gLP-035Biotin-PEG-SC-3400-500mgBiotin-PEG-SC,MW3,400500mgLP-036Biotin-PEG-SC-5000-100mgBiotin-PEG-SC,MW5,000100mgLP-037Biotin-PEG-SCM-3400-100mgBiotin-PEG-SCM,MW3,400100mgLP-037Biotin-PEG-SCM-3400-1gBiotin-PEG-SCM,MW3,4001gLP-037Biotin-PEG-SCM-3400-500mgBiotin-PEG-SCM,MW3,400500mgLP-038Biotin-PEG-SCM-5000-100mgBiotin-PEG-SCM,MW5,000100mgLP-038Biotin-PEG-SCM-5000-1gBiotin-PEG-SCM,MW5,0001gLP-038Biotin-PEG-SCM-5000-500mgBiotin-PEG-SCM,MW5,000500mgLP-039Biotin-PEG-SIL-3400-500mgBiotin-PEG-Silane,MW3,400500mgLP-040Biotin-PEG-SVA-3400-100mgBiotin-PEG-SVA,MW3,400100mgLP-040Biotin-PEG-SVA-3400-1gBiotin-PEG-SVA,MW3,4001gLP-040Biotin-PEG-SVA-3400-500mgBiotin-PEG-SVA,MW3,400500mgLP-041Biotin-PEG-SVA-5000-100mgBiotin-PEG-SVA,MW5,000100mgLP-041Biotin-PEG-SVA-5000-1gBiotin-PEG-SVA,MW5,0001gLP-041Biotin-PEG-SVA-5000-500mgBiotin-PEG-SVA,MW5,000500mgLP-042BOC-NH-PEG-NH2-2000-1gBOC-NH-PEG-Amine,MW2,0001gLP-043BOC-NH-PEG-NH2-3400-1gBOC-NH-PEG-Amine,MW3,4001gLP-043BOC-NH-PEG-NH2-3400-500mgBOC-NH-PEG-Amine,MW3,400500mgLP-044BOC-NH-PEG-NH2-5000-1gBOC-NH-PEG-Amine,MW3,4005gLP-044BOC-NH-PEG-NPC-5000-1gBOC-NH-PEG-NPC,MW5,0001gLP-044BOC-NH-PEG-NPC-5000-500mgBOC-NH-PEG-NPC,MW5,000500mgLP-045BOC-NH-PEG-SC-3400-1gBOC-NH-PEG-SC,MW3,4001gLP-045BOC-NH-PEG-SC-3400-500mgBOC-NH-PEG-SC,MW3,400500mgLP-046BOC-NH-PEG-SC-5000-1gBOC-NH-PEG-SC,MW5,0001gLP-046BOC-NH-PEG-SC-5000-500mgBOC-NH-PEG-SC,MW5,000500mgLP-047BOC-NH-PEG-SCM-1000-1gBOC-NH-PEG-SCM,MW1,0001gLP-047BOC-NH-PEG-SCM-1000-500mgBOC-NH-PEG-SCM,MW1,000500mgLP-048BOC-NH-PEG-SCM-2000-1gBOC-NH-PEG-SCM,MW2,0001gLP-048BOC-NH-PEG-SCM-2000-500mgBOC-NH-PEG-SCM,MW2,000500mgLP-049BOC-NH-PEG-SCM-3400-1gBOC-NH-PEG-SCM,MW3,4001gLP-049BOC-NH-PEG-SCM-3400-500mgBOC-NH-PEG-SCM,MW3,400500mgLP-049BOC-NH-PEG-SCM-3400-5gBOC-NH-PEG-SCM,MW3,4005gLP-050BOC-NH-PEG-SCM-5K-1gBOC-NH-PEG-SCM,MW5,0001gLP-051CM-PEG-CM-1000-1gCarboxymethyl-PEG-Carboxymethyl,MW1,0001gLP-051CM-PEG-CM-1000-5gCarboxymethyl-PEG-Carboxymethyl,MW1,0005gLP-052CM-PEG-CM-10K-1gCarboxymethyl-PEG-Carboxymethyl,MW10kDa1gLP-052CM-PEG-CM-10K-5gCarboxymethyl-PEG-Carboxymethyl,MW10kDa5gLP-053CM-PEG-CM-2000-1gCarboxymethyl-PEG-Carboxymethyl,MW2,0001gLP-053CM-PEG-CM-2000-5gCarboxymethyl-PEG-Carboxymethyl,MW2,0005gLP-054CM-PEG-CM-3400-1gCarboxymethyl-PEG-Carboxymethyl,MW3,4001gLP-054CM-PEG-CM-3400-5gCarboxymethyl-PEG-Carboxymethyl,MW3,4005gLP-055CM-PEG-CM-5000-1gCarboxymethyl-PEG-Carboxymethyl,MW5,0001gLP-055CM-PEG-CM-5000-5gCarboxymethyl-PEG-Carboxymethyl,MW5,0005gLP-056CM-PEG-SCM-35K-1gCarboxymethyl-PEG-SuccinimidylCarboxymethyl,MW35kDa1gLP-056CM-PEG-SCM-35K-5gCarboxymethyl-PEG-SuccinimidylCarboxymethyl,MW35kDa5gLP-057CM-PEG-SH-1000-1gCarboxymethyl-PEG-Thiol,MW1,0001gLP-057CM-PEG-SH-1000-500mgCarboxymethyl-PEG-Thiol,MW1,000500mgLP-058CM-PEG-SH-2000-1gCarboxymethyl-PEG-Thiol,MW2,0001gLP-058CM-PEG-SH-2000-500mgCarboxymethyl-PEG-Thiol,MW2,000500mgLP-059CM-PEG-SH-3400-1gCarboxymethyl-PEG-Thiol,MW3,4001gLP-059CM-PEG-SH-3400-500mgCarboxymethyl-PEG-Thiol,MW3,400500mgLP-060CM-PEG-SH-5000-1gCarboxymethyl-PEG-Thiol,MW5,0001gLP-060CM-PEG-SH-5000-500mgCarboxymethyl-PEG-Thiol,MW5,000500mgLP-061DSPE-PEG-Biotin-3400-1gDSPE-PEG-Biotin,MW3,4001gLP-062DSPE-PEG-MAL-3400-1gDSPE-PEG-Maleimide,MW3,4001gLP-062DSPE-PEG-MAL-3400-500mgDSPE-PEG-Maleimide,MW3,400500mgLP-063DSPE-PEG-NH2-2000-1gDSPE-PEG-NH2,MW2,0001gLP-064EPOX-PEG-EPOX-2K-1gEpoxide-PEG-Epoxide,MW2,0001gLP-064EPOX-PEG-EPOX-2K-5gEpoxide-PEG-Epoxide,MW2,0005gLP-065EPOX-PEG-EPOX-5K-1gEpoxide-PEG-Epoxide,MW5,0001gLP-065EPOX-PEG-EPOX-5K-5gEpoxide-PEG-Epoxide,MW5,0005gLP-066FLUOR-PEG-MAL-3400-1gFluorescein-PEG-MAL,MW3,4001gLP-067FLUOR-PEG-NH2-5000-1gFluorescein-PEG-Amine,MW5,0001gLP-067FLUOR-PEG-NH2-5000-500mgFluorescein-PEG-Amine,MW5,000500mgLP-068FLUOR-PEG-SCM-20K-1gFluorescein-PEG-SCM,MW20kDa1gLP-068FLUOR-PEG-SCM-20K-500mgFluorescein-PEG-SCM,MW20kDa500mgLP-069FLUOR-PEG-SCM-3400-1gFluorescein-PEG-SCM,MW3,4001gLP-069FLUOR-PEG-SCM-3400-500mgFluorescein-PEG-SCM,MW3,400500mgLP-069FLUOR-PEG-SCM-3400-5gFluorescein-PEG-SCM,MW3,4005gLP-070FLUOR-PEG-SCM-5000-1gFluorescein-PEG-SCM,MW5,0001gLP-070FLUOR-PEG-SCM-5000-500mgFluorescein-PEG-SCM,MW5,000500mgLP-071FLUOR-PEG-SVA-3400-1gFluorescein-PEG-SVA,MW3,4001gLP-072FLUOR-PEG-SVA-5000-1gFluorescein-PEG-SVA,MW5,0001gLP-072FLUOR-PEG-SVA-5K-500mgFluorescein-PEG-SVA,MW5,000500mgLP-073FMOC-NH-PEG-CM-3400-1gFMOC-NH-PEG-CM,MW3,4001gLP-074FMOC-NH-PEG-NH2-TFA-1K-1gFMOC-NH-PEG-NH2*TFAsalt,MW1,0001gLP-075FMOC-NH-PEG-NH2-TFA-5K-500mgFMOC-NH-PEG-NH2*TFAsalt,MW5,000500mgLP-076FMOC-NH-PEG-OH-5000-1gFMOC-NH-PEG-OH,MW5,0001gLP-077FMOC-NH-PEG-SCM-2000-1gFMOC-NH-PEG-SCM,MW2,0001gLP-077FMOC-NH-PEG-SCM-2000-500mgFMOC-NH-PEG-SCM,MW2,000500mgLP-078FMOC-NH-PEG-SCM-3400-1gFMOC-NH-PEG-SCM,MW3,4001gLP-078FMOC-NH-PEG-SCM-3400-500mgFMOC-NH-PEG-SCM,MW3,400500mgLP-078FMOC-NH-PEG-SCM-3400-5gFMOC-NH-PEG-SCM,MW3,4005gLP-079FMOC-NH-PEG-SCM-5000-1gFMOC-NH-PEG-SCM,MW5,0001gLP-079FMOC-NH-PEG-SCM-5000-500mgFMOC-NH-PEG-SCM,MW5,000500mgLP-080HO-PEG-CM-3400-1gHO-PEG-CM,MW3,4001gLP-080HO-PEG-CM-3400-500mgHO-PEG-CM,MW3,400500mgLP-080HO-PEG-CM-3400-5gHO-PEG-CM,MW3,4005gLP-081HO-PEG-MAL-3400-1gHO-PEG-MAL,MW3,4001gLP-081HO-PEG-MAL-3400-500mgHO-PEG-MAL,MW3,400500mgLP-082HO-PEG-MAL-5000-1gHO-PEG-MAL,MW5,0001gLP-082HO-PEG-MAL-5000-500mgHO-PEG-MAL,MW5,000500mgLP-083HO-PEG-NH2-1000-1gHO-PEG-NH2,MW1,0001gLP-084HO-PEG-NH2-3400-1gHO-PEG-NH2,MW3,4001gLP-084HO-PEG-NH2-3400-500mgHO-PEG-NH2,MW3,400500mgLP-085HO-PEG-NH2-35K-1gHO-PEG-NH2,MW35kDa1gLP-086HO-PEG-NH2-5000-1gHO-PEG-NH2,MW5,0001gLP-086HO-PEG-NH2-5000-500mgHO-PEG-NH2,MW5,000500mgLP-087HZ-PEG-HZ-2000-1gHydrazide-PEG-Hydrazide,MW2,0001gLP-087HZ-PEG-HZ-3400-1gHydrazide-PEG-Hydrazide,MW3,4001gLP-088MAL-PEG-MAL-10K-1gMaleimide-PEG-Maleimide,MW10kDa1gLP-089MAL-PEG-MAL-2K-1gMaleimide-PEG-Maleimide,MW2,0001gLP-090MAL-PEG-MAL-3400-1gMaleimide-PEG-Maleimide,MW3,4001gLP-090MAL-PEG-MAL-3400-5gMaleimide-PEG-Maleimide,MW3,4005gLP-091MAL-PEG-MAL-5K-1gMaleimide-PEG-Maleimide,MW5,0001gLP-092MAL-PEG-SCM-10kDa-1gMaleimide-PEG-SCM,MW10kDa1gLP-093MAL-PEG-SCM-2000-100mgMaleimide-PEG-SCM,MW2,000100mgLP-093MAL-PEG-SCM-2000-1gMaleimide-PEG-SCM,MW2,0001gLP-094MAL-PEG-SCM-3400-100mgMaleimide-PEG-SCM,MW3,400100mgLP-094MAL-PEG-SCM-3400-1gMaleimide-PEG-SCM,MW3,4001gLP-094MAL-PEG-SCM-3400-500mgMaleimide-PEG-SCM,MW3,400500mgLP-095MAL-PEG-SCM-5000-100mgMaleimide-PEG-SCM,MW5,000100mgLP-095MAL-PEG-SCM-5000-1gMaleimide-PEG-SCM,MW5,0001gLP-096MAL-PEG-SVA-3400-100mgMaleimide-PEG-SuccinimidylValerate,MW3,400100mgLP-096MAL-PEG-SVA-3400-1gMaleimide-PEG-SuccinimidylValerate,MW3,4001gLP-096MAL-PEG-SVA-3400-500mgMaleimide-PEG-SuccinimidylValerate,MW3,400500mgLP-097MPEG-ACRL-10K-1gmPEG-Acrylate,MW10kDa1gLP-097MPEG-ACRL-10K-5gmPEG-Acrylate,MW10kDa5gLP-098MPEG-ACRL-5000-1gmPEG-Acrylate,MW5,0001gLP-098MPEG-ACRL-5000-5gmPEG-Acrylate,MW5,0005gLP-099MPEG-bALD-20K-1gmPEG-Butyraldehyde,MW20kDa1gLP-099MPEG-bALD-20K-5gmPEG-Butyraldehyde,MW20kDa5gLP-100MPEG-bALD-30K-1gmPEG-Butyraldehyde,MW30kDa1gLP-100MPEG-bALD-30K-5gmPEG-Butyraldehyde,MW30kDa5gLP-101MPEG-bALD-5K-1gmPEG-Butyraldehyde,MW5,0001gLP-101MPEG-bALD-5K-5gmPEG-Butyraldehyde,MW5,0005gLP-102MPEG-Biotin-2000-1gmPEG-Biotin,MW2,0001gLP-102MPEG-Biotin-2000-5gmPEG-Biotin,MW2,0005gLP-103MPEG-Biotin-20K-1gmPEG-Biotin,MW20kDa1gLP-104MPEG-Biotin-5000-1gmPEG-Biotin,MW5,0001gLP-104MPEG-Biotin-5000-5gmPEG-Biotin,MW5,0005gLP-105MPEG-CM-10K-1gmPEG-Carboxymethyl,MW10kDa1gLP-105MPEG-CM-10K-5gmPEG-Carboxymethyl,MW10kDa5gLP-106MPEG-CM-2000-1gmPEG-Carboxymethyl,MW2,0001gLP-106MPEG-CM-2000-5gmPEG-Carboxymethyl,MW2,0005gLP-107MPEG-CM-20K-1gmPEG-Carboxymethyl,MW20kDa1gLP-107MPEG-CM-20K-5gmPEG-Carboxymethyl,MW20kDa5gLP-108MPEG-CM-5000-1gmPEG-Carboxymethyl,MW5,0001gLP-108MPEG-CM-5000-5gmPEG-Carboxymethyl,MW5,0005gLP-109MPEG-DSPE-5000-1gmPEG-DSPE,MW5,0001gLP-109MPEG-DSPE-5000-5gmPEG-DSPE,MW5,0005gLP-110MPEG-HZ-10K-1gmPEG-Hydrazide,MW10kDa1gLP-111MPEG-HZ-2000-1gmPEG-Hydrazide,MW2,0001gLP-112MPEG-HZ-20K-1gmPEG-Hydrazide,MW20kDa1gLP-112MPEG-HZ-20K-5gmPEG-Hydrazide,MW20kDa5gLP-113MPEG-HZ-5000-1gmPEG-Hydrazide,MW5,0001gLP-113MPEG-HZ-5000-5gmPEG-Hydrazide,MW5,0005gLP-114MPEG-MAL-10K-1gmPEG-Maleimide,MW10kDa1gLP-114MPEG-MAL-10K-5gmPEG-Maleimide,MW10kDa5gLP-115mPEG-MAL-2000-1gmPEG-Maleimide,MW2,0001gLP-116MPEG-MAL-20K-1gmPEG-Maleimide,MW20kDa1gLP-116MPEG-MAL-20K-5gmPEG-Maleimide,MW20kDa5gLP-117MPEG-MAL-30K-1gmPEG-Maleimide,MW30kDa1gLP-117MPEG-MAL-30K-5gmPEG-Maleimide,MW30kDa5gLP-118MPEG-MAL-5000-1gmPEG-Maleimide,MW5,0001gLP-118MPEG-MAL-5000-5gmPEG-Maleimide,MW5,0005gLP-119MPEG-NH2-1000-1gmPEG-Amine,MW1,0001gLP-119MPEG-NH2-1000-5gmPEG-Amine,MW1,0005gLP-120MPEG-NH2-10K-1gmPEG-Amine,MW10kDa1gLP-120MPEG-NH2-10K-5gmPEG-Amine,MW10kDa5gLP-121MPEG-NH2-2000-1gmPEG-Amine,MW2,0001gLP-121MPEG-NH2-2000-5gmPEG-Amine,MW2,0005gLP-122MPEG-NH2-20K-1gmPEG-Amine,MW20kDa1gLP-122MPEG-NH2-20K-5gmPEG-Amine,MW20kDa5gLP-123MPEG-NH2-30K-1gmPEG-Amine,MW30kDa1gLP-123MPEG-NH2-30K-5gmPEG-Amine,MW30kDa5gLP-124MPEG-NH2-5000-1gmPEG-Amine,MW5,0001gLP-124MPEG-NH2-5000-5gmPEG-Amine,MW5,0005gLP-125MPEG-NH2-550-1gmPEG-Amine,MW5501gLP-125MPEG-NH2-550-5gmPEG-Amine,MW5505gLP-126mPEG-NPC-1000-1gmPEG-NitrophenylCarbonate,MW1,0001gLP-127mPEG-NPC-10K-1gmPEG-NitrophenylCarbonate,MW10kDa1gLP-127mPEG-NPC-10K-5gmPEG-NitrophenylCarbonate,MW10kDa5gLP-128mPEG-NPC-2000-1gmPEG-NitrophenylCarbonate,MW2,0001gLP-129mPEG-NPC-20K-1gmPEG-NitrophenylCarbonate,MW20kDa1gLP-130MPEG-NPC-5000-1gmPEG-NitrophenylCarbonate,MW5,0001gLP-130MPEG-NPC-5000-5gmPEG-NitrophenylCarbonate,MW5,0005gLP-131MPEG-OPSS-10K-1gmPEG-OrthopyridylDisulfide,MW10kDa1gLP-132MPEG-OPSS-2000-1gmPEG-OrthopyridylDisulfide,MW2,0001gLP-133MPEG-OPSS-5000-1gmPEG-OrthopyridylDisulfide,MW5,0001gLP-133MPEG-OPSS-5000-5gmPEG-OrthopyridylDisulfide,MW5,0005gLP-134MPEG-pALD-20K-1gmPEG-Propionaldehyde,MW20kDa1gLP-134MPEG-pALD-20K-5gmPEG-Propionaldehyde,MW20kDa5gLP-135MPEG-pALD-30K-1gmPEG-Propionaldehyde,MW30kDa1gLP-135MPEG-pALD-30K-5gmPEG-Propionaldehyde,MW30kDa5gLP-136MPEG-pALD-5000-1gmPEG-Propionaldehyde,MW5,0001gLP-136MPEG-pALD-5000-5gmPEG-Propionaldehyde,MW5,0005gLP-137MPEG-PLA-5000-1gmPEG-PLA,MW5,000-1gram1gLP-137MPEG-PLA-5000-5gmPEG-PLA,MW5,000-5gram5gLP-138MPEG-SCM-10K-1gmPEG-SCM,MW10kDa1gLP-138MPEG-SCM-10K-5gmPEG-SCM,MW10kDa5gLP-139MPEG-SCM-20K-1gmPEG-SCM,MW20kDa1gLP-139MPEG-SCM-20K-5gmPEG-SCM,MW20kDa5gLP-140mPEG-SCM-2K-1gmPEG-SCM,MW2,0001gLP-141MPEG-SCM-5000-1gmPEG-SCM,MW5,0001gLP-141MPEG-SCM-5000-5gmPEG-SCM,MW5,0005gLP-142MPEG-SG-10K-5gmPEG-SuccinimidylGlutarate,MW10kDa5gLP-143MPEG-SG-2000-1gmPEG-SuccinimidylGlutarate,MW2,0001gLP-143MPEG-SG-2000-5gmPEG-SuccinimidylGlutarate,MW2,0005gLP-144MPEG-SG-20K-1gmPEG-SuccinimidylGlutarate,MW20kDa1gLP-144MPEG-SG-20K-5gmPEG-SuccinimidylGlutarate,MW20kDa5gLP-145MPEG-SG-30K-1gmPEG-SuccinimidylGlutarate,MW30kDa1gLP-145MPEG-SG-30K-5gmPEG-SuccinimidylGlutarate,MW30kDa5gLP-146MPEG-SG-5000-1gmPEG-SuccinimidylGlutarate,MW5,0001gLP-146MPEG-SG-5000-5gmPEG-SuccinimidylGlutarate,MW5,0005gLP-147MPEG-SH-1000-1gmPEG-Thiol,MW1,0001gLP-148MPEG-SH-10K-1gmPEG-Thiol,MW10kDa1gLP-149MPEG-SH-2000-1gmPEG-Thiol,MW2,0001gLP-150MPEG-SH-20K-1gmPEG-Thiol,MW20kDa1gLP-151MPEG-SH-20K-5gmPEG-Thiol,MW20kDa5gLP-151MPEG-SH-5000-1gmPEG-Thiol,MW5,0001gLP-152MPEG-SH-5000-5gmPEG-Thiol,MW5,0005gLP-152MPEG-SIL-1000-1gmPEG-Silane,MW1,0001gLP-153MPEG-SIL-2000-1gmPEG-Silane,MW2,0001gLP-153MPEG-SIL-5000-1gmPEG-Silane,MW5,0001gLP-154MPEG-SIL-5000-5gmPEG-Silane,MW5,0005gLP-154MPEG-SPA-550-1gmPEG-SPA,MW5501gLP-155MPEG-SPA-550-5gmPEG-SPA,MW5505gLP-155MPEG-SS-20K-1gmPEG-SuccinimidylSuccinate,MW20kDa1gLP-156MPEG-SS-20K-5gmPEG-SuccinimidylSuccinate,MW20kDa5gLP-156MPEG-SS-30K-1gmPEG-SuccinimidylSuccinate,MW30kDa1gLP-157MPEG-SS-30K-5gmPEG-SuccinimidylSuccinate,MW30kDa5gLP-157MPEG-SS-5000-1gmPEG-SuccinimidylSuccinate,MW5,0001gLP-158MPEG-SS-5000-5gmPEG-SuccinimidylSuccinate,MW5,0005gLP-158MPEG-SVA-10K-1gmPEG-SuccinimidylValerate,MW10kDa1gLP-159MPEG-SVA-10K-5gmPEG-SuccinimidylValerate,MW10kDa5gLP-159MPEG-SVA-2000-1gmPEG-SuccinimidylValerate,MW2,0001gLP-160MPEG-SVA-2000-5gmPEG-SuccinimidylValerate,MW2,0005gLP-160MPEG-SVA-20K-1gmPEG-SuccinimidylValerate,MW20kDa1gLP-161MPEG-SVA-20K-5gmPEG-SuccinimidylValerate,MW20kDa5gLP-161MPEG-SVA-30K-1gmPEG-SuccinimidylValerate,MW30kDa1gLP-162MPEG-SVA-30K-5gmPEG-SuccinimidylValerate,MW30kDa5gLP-162MPEG-SVA-5000-1gmPEG-SuccinimidylValerate,MW5,0001gLP-163MPEG-SVA-5000-5gmPEG-SuccinimidylValerate,MW5,0005gLP-163MPEG-TOSYL-30K-1gmPEG-Tosylate,MW30kDa1gLP-164MPEG-TOSYL-30K-5gmPEG-Tosylate,MW30kDa5gLP-165NH2-PEG-CM-1000-1gNH2-PEG-CM,MW1,0001gLP-165NH2-PEG-CM-1000-500mgNH2-PEG-CM,MW1,000500mgLP-166NH2-PEG-CM-10kDa-1gNH2-PEG-CM,MW10kDa1gLP-166NH2-PEG-CM-10kDa-500mgNH2-PEG-CM,MW10kDa500mgLP-167NH2-PEG-CM-2000-1gNH2-PEG-CM,MW2,0001gLP-167NH2-PEG-CM-2000-500mgNH2-PEG-CM,MW2,000500mgLP-168NH2-PEG-CM-3400-1gNH2-PEG-CM,MW3,4001gLP-168NH2-PEG-CM-3400-500mgNH2-PEG-CM,MW3,400500mgLP-168NH2-PEG-CM-3400-5gNH2-PEG-CM,MW3,4005gLP-169NH2-PEG-CM-5000-1gNH2-PEG-CM,MW5,0001gLP-169NH2-PEG-CM-5000-500mgNH2-PEG-CM,MW5,000500mgLP-170NH2-PEG-NH2-10K-1gAmine-PEG-Amine,MW10kDa1gLP-170NH2-PEG-NH2-10K-5gAmine-PEG-Amine,MW10kDa5gLP-171NH2-PEG-NH2-1K-1gAmine-PEG-Amine,MW1,0001gLP-171NH2-PEG-NH2-1K-5gAmine-PEG-Amine,MW1,0005gLP-172NH2-PEG-NH2-20K-1gAmine-PEG-Amine,MW20kDa1gLP-172NH2-PEG-NH2-20K-5gAmine-PEG-Amine,MW20kDa5gLP-173NH2-PEG-NH2-2K-1gAmine-PEG-Amine,MW2,0001gLP-174NH2-PEG-NH2-3400-1gAmine-PEG-Amine,MW3,4001gLP-174NH2-PEG-NH2-3400-5gAmine-PEG-Amine,MW3,4005gLP-175NH2-PEG-NH2-35K-1gAmine-PEG-Amine,MW35kDa1gLP-175NH2-PEG-NH2-35K-5gAmine-PEG-Amine,MW35kDa5gLP-176NH2-PEG-NH2-5K-1gAmine-PEG-Amine,MW5,0001gLP-177NH2-PEG-SH-1000-1gNH2-PEG-Thiol,MW1,0001gLP-178NH2-PEG-SH-20K-1gNH2-PEG-Thiol,MW20kDa1gLP-178NH2-PEG-SH-20K-500mgNH2-PEG-Thiol,MW20kDa500mgLP-179NH2-PEG-SH-5000-1gNH2-PEG-Thiol,MW5,0001gLP-179NH2-PEG-SH-5000-500mgNH2-PEG-Thiol,MW5,000500mgLP-180NH2-PEG-VA-3400-1gAmine-PEG-ValericAcid,MW3,4001gLP-180NH2-PEG-VA-3400-500mgAmine-PEG-ValericAcid,MW3,400500mgLP-181NH2-PEG-VA-5K-1gAmine-PEG-ValericAcid,MW5,0001gLP-182NPC-PEG-NPC-2000-1gNPC-PEG-NPC,MW2,0001gLP-183NPC-PEG-NPC-3400-1gNPC-PEG-NPC,MW3,4001gLP-183NPC-PEG-NPC-3400-5gNPC-PEG-NPC,MW3,4005gLP-184OPSS-PEG-CM-5000-1gOPSS-PEG-CM,MW5,0001gLP-185OPSS-PEG-OPSS-10K-1gOPSS-PEG-OPSS,MW10kDa1gLP-186OPSS-PEG-OPSS-2000-1gOPSS-PEG-OPSS,MW2,0001gLP-186OPSS-PEG-OPSS-2000-1gOPSS-PEG-OPSS,MW2,0001gLP-186OPSS-PEG-OPSS-2000-5gOPSS-PEG-OPSS,MW2,0005gLP-187OPSS-PEG-OPSS-3400-1gOPSS-PEG-OPSS,MW3,4001gLP-187OPSS-PEG-OPSS-3400-1gOPSS-PEG-OPSS,MW3,4001gLP-188OPSS-PEG-SCM-3400-1gOPSS-PEG-SCM,MW3,4001gLP-188OPSS-PEG-SCM-3400-500mgOPSS-PEG-SCM,MW3,400500mgLP-189OPSS-PEG-SVA-2000-1gOPSS-PEG-SVA,MW2,0001gLP-190OPSS-PEG-SVA-3400-1gOPSS-PEG-SVA,MW3,4001gLP-190OPSS-PEG-SVA-3400-500mgOPSS-PEG-SVA,MW3,400500mgLP-191OPSS-PEG-SVA-5000-1gOPSS-PEG-SVA,MW5,0001gLP-191OPSS-PEG-SVA-5000-500mgOPSS-PEG-SVA,MW5,000500mgLP-192SCM-PEG-CM-35K-1gSCM-PEG-CM,MW35,0001gLP-192SCM-PEG-CM-35K-5gSCM-PEG-CM,MW35,0005gLP-193SCM-PEG-SCM-3400-1gSCM-PEG-SCM,MW3,4001gLP-193SCM-PEG-SCM-3400-5gSCM-PEG-SCM,MW3,4005gLP-194SC-PEG-CM-1000-1gSC-PEG-CM,MW1,0001gLP-195SC-PEG-CMme-3400-1gSC-PEG-CM(methylester),MW3,4001gLP-195SC-PEG-CMme-3400-500mgSC-PEG-CM(methylester),MW3,400500mgLP-196SG-PEG-SG-10K-1gSG-PEG-SG,MW10kDa1gLP-196SG-PEG-SG-10K-5gSG-PEG-SG,MW10kDa5gLP-197SG-PEG-SG-2000-1gSG-PEG-SG,MW2,0001gLP-198SG-PEG-SG-3400-1gSG-PEG-SG,MW3,4001gLP-198SG-PEG-SG-3400-5gSG-PEG-SG,MW3,4005gLP-199SG-PEG-SG-5K-1gSG-PEG-SG,MW5,0001gLP-199SG-PEG-SG-5K-5gSG-PEG-SG,MW5,0005gLP-200SH-PEG-SH-10K-1gThiol-PEG-Thiol,MW10kDa1gLP-200SH-PEG-SH-10K-5gThiol-PEG-Thiol,MW10kDa5gLP-201SH-PEG-SH-3400-1gThiol-PEG-Thiol,MW3,4001gLP-201SH-PEG-SH-3400-5gThiol-PEG-Thiol,MW3,4005gLP-202SH-PEG-SH-5K-1gThiol-PEG-Thiol,MW5,0001gLP-202SH-PEG-SH-5K-5gThiol-PEG-Thiol,MW5,0005gLP-203SIL-PEG-SIL-3400-1gSilane-PEG-Silane,MW3,4001gLP-204SS-PEG-SS-2000-1gSS-PEG-SS,MW2,0001gLP-205SS-PEG-SS-3400-1gSS-PEG-SS,MW3,4001gLP-205SS-PEG-SS-3400-5gSS-PEG-SS,MW3,4005gLP-206SVA-PEG-SVA-3400-1gSVA-PEG-SVA,MW3,4001gLP-206SVA-PEG-SVA-3400-5gSVA-PEG-SVA,MW3,4005gLP-207SVA-PEG-SVA-5K-1gSVA-PEG-SVA,MW5,0001gLP-207SVA-PEG-SVA-5K-5gSVA-PEG-SVA,MW5,0005gLP-208TOSYL-PEG-TOSYL-35K-1gTosylate-PEG-Tosylate,MW35kDa1gLP-208TOSYL-PEG-TOSYL-35K-5gTosylate-PEG-Tosylate,MW35kDa5gLP-209VA-PEG-VA-20K-1gValericAcid-PEG-ValericAcid,MW20kDa1gLP-209VA-PEG-VA-20K-5gValericAcid-PEG-ValericAcid,MW20kDa5gLP-210VA-PEG-VA-5000-1gValericAcid-PEG-ValericAcid,MW5,0001gLP-210VA-PEG-VA-5000-5gValericAcid-PEG-ValericAcid,MW5,0005g上海西宝生物科技有限公司杨露(6221)13512172575QQ:1916572322俞婵(6512)13817370083QQ:2457655304杨树彦(6236)13788987962QQ:1961275959电话:021-50272975/76/77/78传真:021-50272982E-mail:trade@lifesci9@MSN:lifesci9@Http://地址:上海市张江高科技园区毕升路299弄11#502)