Microcystin-LA
Microcystin-LAProductSpecificationFORMULA:C46H67N7O12MW:910.0CASNUMBER:96180-79-9RTECS:GT2805000SOURCE/HOST:IsolatedfromMicrocystisaeruginosa.PURITY:≥95%(HPLC)APPEARANCE:Whitishfilmadheredtoinsideofthevial.SOLUBILITY:Solublein100%ethanolormethanol.SHIPPING:AMBIENTLONGTERMSTORAGE:-20°CUSE/STABILITY:Stocksoluti***arestableforupto6monthswhenstoredat-20°C.UnstableatpH>7.7.HANDLING:Formaximumproductrecoveryafterthawing,centrifugethevialbeforeopeningthecap.HAZARD:MAYBECARCINOGENIC.VERYTOXIC.HIGHLYIRRITANT.ProductDescriptionAnalogofmicrocystin-LR(Prod.No.ALX-350-096)withAlasubstitutedinplaceofArg.Inhibitsproteinphosphatase2A(PP2A)andproteinphosphatase3(PP3)morepotentlythanproteinphosphatase1(PP1).Ozonationoftoxicwatersamplesdoesleadtoacompletelossofthemicrocystinsandtheirtoxicity.ProductSpecificLiteratureReferencesThestructureofcyanoginosin-LA,acyclicheptapeptidetoxinfromthecyanobacteriumMicrocystisaeruginosa:D.P.Botesetal.;J.Chem.Soc.1,2311(1984)MicrocystincompositionofanaxenicclonalstrainofMicrocystisviridisandMicrocystisviridis-containingwaterbloomsinJapanesefreshwaters:K.KayaandM.M.Watanabe;J.App.Phycol.2007,173(1990)Thedesign,synthesis,andbiologicalevaluationofanaloguesoftheserine-threonineproteinphosphatase1and2AselectiveinhibitormicrocystinLA:rationalmodificati***impartingPP1selectivity:J.B.Aggen,etal.;Bioorg.Med.Chem.7,543(1999)AbstractTreatmentopti***formicrocystintoxins:similaritiesanddifferencesbetweenvariants:G.Newcombe,etal.;Environ.Technol.24,299(2003)AbstractDecreaseintoxicityofmicrocystinsLAandLRindrinkingwaterbyozonation:S.Brooke,etal.;Toxicon.48,1054(2006)Abstract~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~如有更多其它***产品需求与查询,请及时接洽:info@express-cn.com或在我公司查询主页客户留言处(http://www.express-cn.com/expressgb/m)留下您的查询内容,我们即会在当天为您作出回复。在线***:***:1069267096MSN:liyuqiu1983@cindylee-1981@总机:Tel:010-60206266(北京)传真/Fax:010-60206773(北京)----------------------------------------------------------------------------------------------------------------------------云南***:Tel:871-8301322871-8331318871-8331455(昆明)传真/Fax:871-8301933www.express-cn.com)