醛糖还原酶AldoseReductase,recombinantWakoStoragecondition:Keepat-20degreesC.规格:0.4UNITSSummaryThisproductisforresearchuseonly.Donotadministerittohuman.Origin:HumanmusclecellSpecificactivity:1.4-1.6units/mgConcentration:1units/mLMW:approx.36,000Preparation:Theenzymeisdissolvedin5mMDTT,50%glycerinand50mMSodiumphosphatebuffersolution(pH7.0).AldoseReductaseispurifiedfromtheculturemediumcontainingbaculovirus-insectcellline32dgeneexpressionsystem.cDNAcontainingtheentireproteincodingregionisexpressed,andtheenzymeexhibitsthesamepropertiesandcharacteristicsofhumanmuscleandretina.AldoseReductasecatalyzesthereductionofglucosetosorbitol.Sorbitolissubsequentlyconvertedtofructosebysorbitoldehydrogenase.Thesetwoenzymesarekeycomponentsofthepolyolpathway,thealternaterouteofglucosemetaboli***.Itissuggestedthataldosereductaseisinvolvedinthepathogenesisofdiabeticcomplicati***andtheinhibitorscontinuetobedevelopedatavigorouspace.[Reference]Nishimura,C.etal.:BiochimBiophys.Acta.,1078,171(1991).~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~如有更多其它***产品需求与查询,请及时接洽：info@express-cn.com或在我公司查询主页客户留言处（http://www.express-cn.com/expressgb/m）留下您的查询内容，我们即会在当天为您作出回复。伊普瑞斯科技有限公司info@express-cn.com总机：010-60206266传真：010-60206773www.express-cn.com)