Clickchemistry点击化学链接化学点击化学工具:DBCO，TCO，四嗪，叠氮化物，炔烃和相关***。DBCOReagentsThedibenzocyclooctynegroup(DBCO)allowsCopper-freeClickChemistrytobedonewithlivecells,wholeorgani***s,andnon-livingsamples.DBCO-C6-NHSEsterDBCO-C6-NHSEsterisanamine-reactivebuildingblockusedformodificationofamine-containingmoleculeinorganicmedia.DBCO-NHSEsterDBCO-NHSEsterisanamine-reactivebuildingblockusedformodificationofamine-containingmoleculeinorganicmedia.DBCO-Sulfo-NHSEsterDBCO-Sulfo-NHSEsteriswater-solublereagentthatenablessimpleandefficientlabelingofantibodies,proteinsandanyotherprimaryamine-containingmacromoleculeswithDBCOmoietyin100%aqueousbuffers.DBCO-PEG4-NHSEsterDBCO-PEG4-NHSEsterreactsspecificallyandefficientlywithaprimaryamine(e.g.,sidechainoflysineresiduesoraminosilane-coatedsurfaces)atpH7-9toformacovalentbond.DBCO-PEG5-NHSEsterDBCO-PEG5-NHSEsterreactsspecificallyandefficientlywithaprimaryamine(e.g.,sidechainoflysineresiduesoraminosilane-coatedsurfaces)atpH7-9toformacovalentbond.DBCO-PEG13-NHSEsterDBCO-PEG13-NHSEsterreactsspecificallyandefficientlywithaprimaryamine(e.g.,sidechainoflysineresiduesoraminosilane-coatedsurfaces)atpH7-9toformacovalentbond.Thehydrophilicpolyethyleneglycol(PEG)spacerarmimpartswatersolubilityandprovidesalongandflexibleconnectionthatminimizessterichindranceinvolvedwithligationtocomplementaryazide-containingmolecules.PCDBCO-NHSEsterPhotocle***ableDBCO-NHSesterreagentcontainsanaminereactivegrouplinkedtoDBCOmoietythroughaspacerarmcontainingaphotocle***ablemoiety.DBCO-C6-AcidDBCO-C6-AcidisananalogofDBCO-Acidwithextended6-carbonatomspacerarm.DBCO-AcidDBCO-Acidisanamine-reactivenon-activatedbuildingblockusedforderivatizingamine-containingmoleculeinthepresenceofactivators(e.g.EDC,orHATU)throughastableamidebond.DBCO-PEG5-AcidDBCO-PEG5-Acidisanamine-reactive,non-activatedbuildingblockwithenhancedsolubilityinaqueousmediausedforderivatizingamine-containingmoleculeinthepresenceofactivators(e.g.EDC,orHATU)throughastableamidebond.DBCO-AmineDBCO-AmineisasimpleDBCO-containingbuildingblockusedtoderivatizecarboxylgroupsinthepresenceofactivators(e.g.EDC,orDCC)oractivatedesters(e.g.NHSesters)withDBCOmoietythroughastableamidebond.DBCO-PEG3-AmineDBCO-PEG3-Amineisacarboxyl-reactivebuildingblockwithenhancedsolubilityinaqueousmediausedtoderivatizecarboxylgroupsinthepresenceofactivators(e.g.EDC,orDCC)oractivatedesters(e.g.NHSesters)throughastableamidebond.SulfoDBCO-AmineSulfoDBCO-Amineisawater-solublebuildingblockusedtoderivatizecarboxyl-containingmoleculesoractivatedesters(e.g.NHSesters)withDBCOmoietythroughastableamidebond.ThehydrophilicsulfonatedspacerarmgreatlyimproveswatersolubilityofDBCOderivatizedmolecules,inmanycasesmakingitcompletelysolubleinaqueousmedia.SulfoDBCO-PEG4-AmineSulfoDBCO-PEG4-Amineisawater-solublereagentusedtoderivatizecarboxyl-containingmoleculesoractivatedesters(e.g.NHSesters)withDBCOmoietythroughastableamidebond.DBCO-MaleimideDBCO-MaleimideenablessimpleandefficientincorporationofDBCOmoietyontocysteine-containingpeptidesorotherthiol-containingmolecules.DBCO-PEG4-MaleimideDBCO-PEG4-MaleimideenablessimpleandefficientincorporationofDBCOmoietyontoantibodies,cysteine-containingpeptidesandotherthiol-containingmolecules.Bis-sulfone-PEG4-DBCOBis-sulfone-PEG4-DBCOisabis-alkylatinglabelingreagentthatenablessite-specificincorporationofDBCOmoietyontoantibodiestoformwell-definedconjugates.ThioLinker-DBCOThioLinkerTM-DCBOisawater-solublebis-alkylatinglabelingreagentenablessite-specificincorporationofDBCOmoietyontoantibodiesinwell-definedfashion.MB488DBCOMB™488DBCOisabright,greenfluorescentprobewithexcitationideallysuitedforthe488nmlaserline.MB543DBCOMB™543DBCOisanorangecoloredfluorescentprobewithabsorptionandemissionmaximaat544and560nm,respectively.MB594DBCOMB™594isabright,redfluorescentprobewithabsorptionandemissionmaximasimilartoTexasReddyeorAlexaFluor594®.Carboxyrhodamine110DBCOCarboxyrhodamine110DBCOdyereactswithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.TAMRADBCOTAMRADBCOdyereactswithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.Cy3DBCOCy3DBCOdyereactswithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.Cy5DBCOCy5DBCOdyereactswithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.Cy5.5DBCOCy5.5DBCOdyereactswithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.Cy7DBCOCy7DBCOdyereactswithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.DBCO-PEG4-BiotinDBCO-PEG4-Biotinreactswithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.WSDBCO-BiotinAwater-soluble,azide-reactivebiotinylationreagentWSDBCO-Bitoinreactswithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazole.DBCO-PEG4-DesthiobiotinDesthiobiotinisasingle-ring,sulfur-freeanalogofbiotinthatbindstostrept***idinwithnearlyequalspecificitybutlessaffinitythanbiotin(Kd=1011vs.1015M,respectively).DdeBiotin-DBCODdeBiotin-DBCOisanazide-reactivebiotinprobethatallowsforefficientreleaseofthecapturedbiomoleculesfromstrept***idin.PCDBCO-BiotinPCBiotin-DBCOisanazide-reactivephotoclevablebiotinprobethatallowsforreagent-freereleaseofthecapturedbiomoleculesfromstrept***idin.WS-PCDBCO-BiotinWS-PCBiotin-DBCOiswatersoluble,azide-reactivephotoclevablebiotinprobethatallowsforreagent-freereleaseofthecapturedbiomoleculesfromstrept***idin.DiazoBiotin-DBCODiazoBiotin-DBCOcontainsabiotinmoietylinkedtoanDBCOgroupthroughasodiumdithionite(Na2S2O4)cle***ablediazolinker.DBCO-mPEG,5kDaDBCO-activatedPEGylationreagentsreactwithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperaturesDBCO-mPEG,10kDaDBCO-activatedPEGylationreagentsreactwithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.DBCO-mPEG,20kDaDBCO-activatedPEGylationreagentsreactwithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.DBCO-mPEG,30kDaDBCO-activatedPEGylationreagentsreactwithazidesviaacopper-free“clickchemistry”reactiontoformastabletriazoleanddoesnotrequireCu-catalystorelevatedtemperatures.DBCO-PEG12-MMAEDBCO-containingauristatindrugusedtocreateantibody-drugconjugatesviaSPAACreaction.Methyltetrazine-DBCOHeterobifunctionalreagentsusedforconvertingazido-containingpeptidesorproteinintotetrazine-modifiedpeptidesorproteinwithouttheneedforcatalystoraxillaryreagents.Methyltetrazine-PEG12-DBCOHeterobifunctionalreagentsusedforconvertingazido-containingpeptidesorproteinintotetrazine-modifiedpeptidesorproteinwithouttheneedforcatalystoraxillaryreagents.DBCO-PEG4-DBCODBCO-PEG4-DBCOisahomobifunctionalazide-to-azidecross-linker.TCO-PEG12-DBCOHeterobifunctionalreagentsareusedforconvertingazido-containingbiomoleculesintoTCO-modifiedbiomolecules.DBCO-PEG4-HydroxylAmodificationreagentcontainingalong4-unitpolyethyleneglycol(PEG4)spacerarmandaterminalprimaryhydroxylgroup.TetrazineReagentsTetrazine-containingreagentsaresuitablefortheintroductionofafunctionalgroup(e.g.AmineorNHSEster)toCyclooctene-labeledmoleculesviaCu-freeClickChemistryanTetrazinegrouptovarioTetrazine-NHSEsterAnamine-reactivebuildingblockwithexceptionalkinetics.Methyltetrazine-NHSEsterAnamine-reactivebuildingblockTetrazine-Sulfo-NHSEsterAwater-solublereagentforlabelingantibodies,proteinsandothermoleculescontainingprimaryamines.Methyltetrazine-Sulfo-NHSEsterAwater-solubleamine-reactivelabelingreagentTetrazine-PEG5-NHSEsterAnamine-reactivelabelingreagentswithenhancedreactivityandwatersolubility.Methyltetrazine-PEG4-NHSEsterAnamine-reactivelabelingreagentswithenhancedstabilityandwatersolubilityMethyltetrazine-PEG5-NHSEsterAnamine-reactivelabelingreagentwithhydrophilicPEG5spacerarmMethyltetrazine-PEG4-Sulfo-NHSEsterAwater-solublereagentforlabelingantibodies,proteinsandothermoleculescontainingprimaryaminesMethyltetrazine-AcidAnamine-reactive,non-activatedbuildingblock.Tetrazine-AcidAnamine-reactive,non-activatedbuildingblockwithexceptionalkinetics.Methyltetrazine-PEG4-AcidAnamine-reactive,non-activatedbuildingblockwithenhancedstabilityandwatersolubility.PCMethyltetrazine-NHSEsterAnamine-reactive,photocle***ablelabelingreagent.Methyltetrazine-AmineAcarboxyl-reactivebuildingblockcontainingtetrazinemoiety.Tetrazine-AmineAcarboxyl-reactivebuildingblockwithexceptionalkinetics.Methyltetrazine-PropylamineAcarboxyl-reactivebuildingblockwithenhancedstability.Methyltetrazine-PEG4-AmineAcarboxyl-reactivebuildingblockwithenhancedstabilityandwatersolubility.Methyltetrazine-PEG4-MaleimideAmid-length,sulfhydryl-reactivelabelingreagentwithenhancedwater-solubilityprovidedbyaPEG4spacer.Bis-sulfone-PEG4-TetrazineAbis-alkylatingreagentusedtointroducetetrazinemoietyontoantibodyinwell-definedfashion.ThioLinker-TetrazineAwater-soluble,thiol-reactive,bis-alkylatinglabelingreagent.Methyltetrazine-DBCOAwater-solubleazide-to-TCOheterobifunctionalcrosslinkerMethyltetrazine-PEG12-DBCOAnazide-to-TCOheterobifunctionalcrosslinkerwithahydrophilicPEG12spacerarmMethyltetrazine-PEG4-AlkyneHeterobifunctionalreagentactivatedwithterminalalkynegroupandmethyltetrazinemoiety.Methyltetrazine-PEG4-AzideAnalkyne-to-TCOheterobifunctionalcrosslinkerwithahydrophilicPEG4spacerarm.Methyltetrazine-mPEG,5kDa5kDa,methyltetrazine-activatedPEGylationreagent.Methyltetrazine-mPEG,10kDa10kDa,methyltetrazine-activatedPEGylationreagent.Methyltetrazine-mPEG,20kDa20kDa,Methyltetrazine-activatedPEGylationreagent.Methyltetrazine-mPEG,30kDa30kDa,Methyltetrazine-activatedPEGylationreagent.Biotin-PEG4-MethyltetrazineAmethyltetrazine-activatedbiotinylationreagentwithahydrophilicPEG4spacerarm.Cy3TetrazineAtetrazine-activatedCy5dye.Cy3MethyltetrazineAmethyltetrazine-activatedCy3dyeforchemoselectivelabelinganddetectionofTCO-taggedmolecules.TAMRATetrazineAnorange-to-redfluorescence-emitting,tetrazine-activatedprobe.TAMRAMethyltetrazineAnorange-to-redfluorescence-emitting,methyltetrazine-activatedprobe.Cy5TetrazineAtetrazine-activatedCy5dye.Cy5MethyltetrazineAmethyltetrazine-activatedCy5dyeforchemoselectivelabelinganddetectionofTCO-taggedmolecules.Cy7MethyltetrazineAwater-soluble,tetrazine-activatedNIRprobe.Tetrazine-PEG4-NOTAMPEG-Tetrazine***聚乙二醇-四嗪磺基MPEG-Tetrazine***聚乙二醇-四嗪磺基是YARE-PEG旗下高质量产品AzideReagentsAzido-containingbuildingblocks,labelingreagents,haptens,andfluorescentprobesPCBiotin-AzideAnazide-activatedphotoclevablebiotinprobe.PCAzido-NHSEsterAnamine-reactive,photocle***ablelabelingreagent.Azido-PropylamineAcarboxyl-reactivebuildingblock.AlkyneReagentsAlkyne-basedlabelingreagents,fluorescentprobesandhaptensforCu-catalyzedclickchemistryPropargyl-NHSEsterAnamine-reactivebuildingblock.PCAlkyne-NHSEsterAnamine-reactive,photocle***ablelabelingreagent.Propargyl-MaleimideAmaleimide-activated,buildingblock.PCBiotin-AlkyneAnazide-activatedphotoclevablebiotinprobeDdeBiotin-AlkyneAnazide-reactive,hydrazine-cle***ablebiotinprobe.DiolBiotin-AlkyneAnazide-reactive,sodiumperiodatecle***ablebiotinprobe.DiazoBiotin-AlkyneAnazide-reactive,sodiumdithionitecle***ablebiotinylationreagent.Alkyne-PEG-Alkyne炔烃-聚乙二醇-炔烃Alkyne-PEG-Alkyne炔烃-聚乙二醇-炔烃是YARE-PEG旗下高质量产品TCOReagentsTrans-Cyclooctene(TCO)-basedlabelingreagents,buildingblocks,andcrosslinkersTCO-NHSEsterAnamine-reactive,succinimidylcarbonate/NHSfunctionalizedcyclooctenebuildingblockTCO-PNBEsterAnamine-reactive,cyclooctene-containingbuildingblock.TCO-PEG4-NHSEsterAnamine-reactivelabelingreagentswithenhancedsolubilityinaqueousbuffersTCO-PEG12-NHSEsterAmine-reactivelabelingreagentswithextendedPEG12spacerarmTCO-PEG4-AcidAmine-reactive,non-activatedbuildingblockwithenhancedsolubilityinaqueousbuffersTCO-PEG3-MaleimideAsulfhydryl-reactivelabelingreagentwithhydrophilicPEG4spacerarm.Cy5-TCOATCO-activatedCy5dye.TCO-AmineHClSaltAcarboxyl-reactivebuildingblock.TCO-PEG3-AmineAcarbonyl-reactivebuildingblockwithenhancedsolubilityinaqueousmedia.TCO-PEG12-DBCOAnazide-to-tetrazineheterobifunctionalcross-linkerwithahydrophilicPEG12spacerarmMPEG-TCOMethoxypolyethyleneglycol-TotalCostofOwnershipMPEG-TCOClickchemistry点击化学链接化学关于YARE：YARE-PEG修饰性PEG产品特点及技术优势：我们已经为我们的客户提供了十年的PEG修饰剂服务，我们一直致力于降***格，提高品质！1、提供多种官能团修饰，性能好，纯度高，产品分子量可定制，产品聚合分散度（PDI）小于1.05；2、生产工艺简化，杂质低，品质稳定；3、批量生产，成本可控；4、可提供2000多种产品规格；5、其他特殊规格可提供定制。Clickchemistry点击化学链接化学--------------------------------------------------------------------------------------液体处理,移液器,移液枪,手动移液器,可调移液枪,微量移液,大容量移液,8道移液器,12道移液枪,多道移液器,电动移液枪,移液工作站,移液管,巴斯德吸管,巴氏管,助吸器,瓶口分液器,移液器支架,原装吸头,盒装管嘴,吸头盒,移液器维修,移液枪校准,,Genex,Biohit,百得,Sartorius,赛多利斯,Proline,mLINE,Tacta,ePet,eLINE,Picus,MidiPlus,Dispenser,Gilson,吉尔森,Pipetman,Eppendorf,艾本德,Researchplus,DragonLab,大龙,TopPette,Thermo,Fisher,热电,Finnpipette,Brand,普兰德,Transferpette,Rainin,梅特勒,瑞宁,pipet-Lite,Socorex-----------------------------------------------------------PEG修饰剂,聚乙二醇修饰剂,PEG衍生物,聚乙二醇衍生物,单官能团PEG,PEG-NH2,PEG-COOH,PEG-SH,PEG-NHS,PEG-SC,PEG-MAL,PEG-N3,PEG-SPA,PEG-ALD,PEG-Silane,PEG-Hydrazide,PEG-Alkyne,双官能团PEG,NH2-PEG-NH2,COOH-PEG-COOH,Mal-PEG-Mal,NHS-PEG-NHS,NH2-PEG-COOH,Boc-NH-PEG-OH,FMOC-NH-PEG-COOH,NH2-PEG-OH,SH-PEG-COOH,SH-PEG-NH2,MAL-PEG-NHS,Biotin-PEG-NH2,多臂PEG,4臂PEG,6臂PEG,8臂PEG,4arm,6arm,8arm,4arm-PEG-NH2,4arm-PEG-COOH,4arm-PEG-SH,8Arm-PEG-SG,短链PEG,单分散PEG,Boc-NH-PEG2-NH2,Boc-NH-PEG2-COOH,SH-PEG3-NH2,磷脂PEG,PEG-PE,mPEG-DSPE,DSPE-PEG-NH2,DSPE-PEG-COOH,DSPE-PEG-Biotin,DSPE-PEG-Mal,聚乳酸PEG,PEG-PLA,PEG-PLGA,PLGA-PEG-PLGA,PLA-PEG-PLA,PLGA-PEG-COOH,PLGA-PEG-NH2,PLGA-PEG-FA,CY7-PEG-NH2,FITC-PEG-NH2,cy5-PEG-DSPE,cy3-PEG-DSPE,温敏水凝胶,NANOCS,ProChimia,Surfaces,Rapp-polymere,Laysan,LaysanBio,Creative,PEGWorks,SunBio,BroadPharm,POLYPURE,NOF,QUANTA,Chemicell,Celares,BioVectra-----------------------------------------------------------2ml透明棕色进样瓶,样品瓶,顶空瓶,螺口瓶,液相瓶,玻璃瓶,解析瓶,储存瓶,液体储存瓶,样品瓶架,进样瓶架,解析瓶架,储存瓶架,样品瓶盒,储存瓶盒,针式过滤器,针头过滤器,针筒式滤头,水系,有机相,微孔滤膜,过滤头,津腾,滤头,尼龙66,PES,PTFE,色谱柱,HPLC,液相色谱,气相色谱,内插管,***灯,检测器,Agilent,安捷伦,Waters,沃特世,岛津-----------------------------------------------------------短型玻璃巴斯德吸管,长型玻璃巴斯德吸管,加长巴氏吸管,巴斯德滴管,巴氏滴管,取样管,吸管消毒桶,吸管灭菌桶,移液管消毒罐,滴管灭菌罐,硅胶胶头,吸管胶头,滴管皮头,硅胶吸球,硅胶头,硅胶帽,巴斯德管头,一次性塑料巴斯德吸管,定制玻璃巴斯德吸管-----------------------------------------------------------标准品,对照品,NIBSC标准品,抗原,***,标品,英国***生物标准与检定所标品,美国药典,USP,欧洲药典,EP,加拿大TRC,中检所-----------------------------------------------------------聚乙二醇修饰化学和PEG修饰剂选择指南移液器的日常清洗和维护***样品瓶和隔垫的选择指南)